Can You Take Magnesium and Vitamin C Together?

Short answer: Yes. Magnesium and vitamin C can be taken together and there is no interaction to worry about at everyday amounts. They do completely different jobs, they are both water-soluble, and they sit together in plenty of balanced daily formulas. No spacing required.

What each one does

Magnesium helps muscles and nerves work like they should, and contributes to the reduction of tiredness and fatigue. Vitamin C helps your body build collagen for skin that works like it should. Those are two separate maintenance roles — one structural and nerve-related, one about collagen formation — so there is no overlap and nothing competing.

Is there an interaction?

Not at the amounts found in daily supplements. Both are water-soluble, and neither blocks the other's absorption. You will occasionally see the two mentioned together in discussions of very high doses of either, but that is a different situation from a sensible daily amount of each in one formula. For everyday intake, taking them at the same time is fine.

The practical way to take them

Both are comfortable with or without food, though taking magnesium alongside something to eat suits some people better if they find it sits heavily on an empty stomach. Vitamin C is water-soluble, so what your body does not use is simply passed out — which is another reason a steady daily amount beats an occasional large one. As with most nutrients, consistency matters far more than the exact hour.

What about other medications?

Magnesium is the one worth mentioning to a pharmacist if you take prescription medication, because it is generally advised to space magnesium apart from certain antibiotics and from levothyroxine. That is about magnesium and the medication, not about vitamin C. If you take anything regularly, run your full supplement list past your pharmacist or prescriber.

Magnesium and vitamin C in Vyelle

Vyelle Daily Renewal contains magnesium (300 mg, as bisglycinate) and vitamin C (200 mg) together in one once-daily drink, with every dose disclosed on the label. Magnesium helps muscles and nerves work like they should; vitamin C helps your body build collagen for skin that works like it should. Read more on magnesium for women over 50 and vitamin C and collagen formation, check what not to take with magnesium, or view the full ingredient list.

Related questions

Does vitamin C affect magnesium absorption?

Not meaningfully at everyday supplement amounts. They are both water-soluble and handled separately, so taking them at the same time does not reduce how much of either you absorb.

Should you take magnesium and vitamin C at different times?

There is no need. They appear together in many balanced formulas and are commonly taken in a single serving. Take them when you will actually remember — consistency is the part that matters.

Can you take too much of either?

Both have sensible upper limits, and more is not better. Large amounts of magnesium can be unsettling for the digestion, and vitamin C is water-soluble so excess is largely passed out rather than stored. Modest daily amounts, taken consistently, is the approach that makes sense — check combined totals with your provider if you take extra on top of a daily formula.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This page is general information, not medical advice; consult your healthcare provider before starting any new supplement, especially if you take prescription medication.